Loading clinical trials...

Ultrasound Guided Radiofrequency Ablation of the Occipital Nerve | Clinical Trials | Clareo Health

RECRUITINGNA

Ultrasound Guided Radiofrequency Ablation of the Occipital Nerve

NCT06583122•University of Kansas Medical Center

Summary

Study an ultrasound guided approach to radiofrequency ablation of the occipital nerve that makes it possible to see the needle during treatment procedure. It is hoped this will reduce the amount of pain after the standard of care procedure.

Eligibility

Age

18 - 80 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patients between the ages of 18-80 with a diagnosis of occipital neuralgia or migraine overlying the occipital region.
•A diagnosis of occipital neuralgia will be based on the International Classification of Headache Disorders (ICHD), whose criteria include: paroxysmal stabbing pain in the distribution of the GON, tenderness over the affected nerve, and relief of pain for at least 3 hours after bupivacaine local anesthetic block of the affected nerve.
•Patients may also be included if they have a diagnosis of migraine based on the ICHD criteria with predominance of pain over the occipital region that responded to occipital nerve block.
•Patients must have failed oral medications including NSAIDs, opioids, and anticonvulsants for the management of their pain.
•Failed treatment will be \<50% pain reduction with oral medication.
•Patients must report headache frequency of at least 10 days per month.

Exclusion Criteria

•Patients will be excluded from the trial if they have an unstable medical or psychological condition,
•are pregnant,
•have an implanted cardiac pacemaker or defibrillator that could not be disabled,
•have had a craniotomy or scar tissue overlying the site from a previous surgery,
•have a history of cervical spine fusion,
•have evidence of elevated ICP or intracranial tumor,
•or have previous RFA treatment of the greater or lesser occipital nerve.

Locations (1)

University of Kansas Medical Center

Kansas City, Kansas, United States

Key Dates

Start Date

July 1, 2022

Primary Completion Date

December 30, 2025

Completion Date

December 31, 2026

Last Updated

April 9, 2025

Enrollment

ESTIMATED participants

Conditions

Nerve Pain

Interventions

Ultrasound Guided Approach

PROCEDURE

Contacts

Timothy Sowder, MD

CONTACT

913-588-6670 tsowder@kumc.edu

Manuel Clark

CONTACT

913-945-5763 mclark16@kumc.edu

Prevalence of Muscle and Nerve and Joint Pain

NCT06402448

Muscle PainJoint Pain+1 more

View study

ACTIVE_NOT_RECRUITINGNA

Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends

NCT04865679

Symptomatic NeuromaAmputation+1 more

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 9, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Ultrasound Guided Radiofrequency Ablation of the Occipital Nerve

Inclusion Criteria

Exclusion Criteria

Prevalence of Muscle and Nerve and Joint Pain

Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends

Study of AxoGuard® Nerve Cap and Neurectomy for Treatment of Symptomatic Neuroma & Prevention of Recurrent Neuroma Pain

Triple Injection Peri-sartorius (TIPS) Block

Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures

A Study To Assess The Ability Of A Crossover Study Design To Detect The Efficacy Of Pregabalin In Post-Traumatic Neuropathic Pain Patients