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RECRUITINGPHASE4

Comparison of Compounded Topical Anesthetics

Comparison of Compounded Topical Anesthetics for Pain Relief of Intense Pulsed Light, Pulse Dye Laser, and Microneedling Treatments

NCT06569537•Dartmouth-Hitchcock Medical Center

View on ClinicalTrials.gov

Summary

The primary objective for this pilot study is to evaluate the efficacy of the compounded topical anesthetic Benzocaine 20%/ Lidocaine 8%/Tetracaine 4% (BLT) compared to 4% Lidocaine topical in providing relief of pain during IPL, PDL, and microneedling procedures.

Eligibility

Age

18 - 75 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Men and women over 18, but not more than 75 years of age.
•Patients who have a regularly scheduled dermatology appointment for Intense Pulse Light (IPL), Pulse Dye Laser (PDL), or microneedling.

Exclusion Criteria

•Any subject who has a previous history of allergy, sensitivity, and contraindication to benzocaine, lidocaine, or tetracaine.
•Patients with cardiac/respiratory disease, seizure disorder, or neuropathies.
•Patients who are under treatment for a dermatologic condition that may interfere with the evaluation of the study.
•Pregnant women and women who are breastfeeding.
•Patients who report concurrent use of anxiolytics or opiates, which may interfere with the interpretation of results.

Locations (1)

Dartmouth Hitchcock Dermatology Clinic

Lebanon, New Hampshire, United States

Key Dates

Start Date

October 22, 2024

Primary Completion Date

January 1, 2026

Completion Date

January 1, 2026

Last Updated

December 16, 2025

Enrollment

ESTIMATED participants

Conditions

Procedural Pain

Interventions

Lidocaine topical

DRUG

BLT

DRUG

Contacts

Nardin Awad, DO

CONTACT

6036532209 nardin.awad@hitchcock.org

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 16, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Comparison of Compounded Topical Anesthetics

Inclusion Criteria

Exclusion Criteria

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