female patients =\> 18 years of age at the time of consent
Can provide written informed consent
Have an ovarian cyst or adnexal mass (simple, complex, or solid ovarian/pelvic mass) identified through imaging examination (e.g. transvaginal ultrasound - TVU) that requires surgery, but have not yet undergone this surgery
You may not be if
Any prior confirmed diagnosis of, or treatment for, ovarian cancer
Any prior surgery resulting in removal of both ovaries
Prior history of gynecological malignancy (within last 2 years)
Prior history of melanoma (within last 2 years)
Prior treatment (within 12 months of sample collection) with chemotherapy, radiotherapy or immunotherapy
Immune-compromised. Definition: those whose weakened immune system may render them more susceptible to infection, illness, or complications. These may include patients with immune-suppressive conditions (e.g. HIV/AIDS), patients undergoing immuno-, chemo- or radio-therapy (within the last 12 months) for any reason, receiving immune suppressive therapies (e.g. transplant recipients, individuals with known autoimmune disease), or with a primary immunodeficiency disorder (e.g. Lupus).
Pregnant currently or within the last 3 months based on participant self-report