Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP

Study Description: This protocol describes the screening and evaluation process used by the National Institute on Drug Abuse (NIDA) Intramural Research Program (IRP) to assess eligibility of individuals interested in enrolling in other NIDA IRP clinical research protocols. This protocol and clinical research protocols conducted at the NIDA IRP seek to improve understanding about of the nature of alcohol and Substance Use Disorders (hereby referenced as SUD, inclusive of alcohol use disorder), determine the potential use of novel SUD therapies and establish the effects of SUD on the development, maturation, function, and structure of the body s organ systems. Objectives: Primary Objective: -To provide an initial clinical and general evaluation of participants to assess eligibility for potential inclusion into other clinical research protocols at the NIDA IRP. Secondary Objectives: * To use the data collected for the Primary Objective toward the development and execution of hypotheses-driven and hypotheses-generating analyses. * To create a registry of participants that may be interested in and eligible to enroll/re-enroll in NIDA IRP clinical research protocols. Endpoints: Primary Endpoint: -Screening, evaluation, and assessment for eligibility to participate in other NIDA clinical research protocols. Secondary Endpoints: -Use the data collected for the primary endpoint to conduct future research to further characterize and understand alcohol and drug use, addiction, abstinence, and other outcomes in people with and without SUD