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Evaluation of Nasal Non Invasive Ventilation Modalities in Management of Neonates With Respiratory Distress Using Lung Ultrasound
This study aims to evaluate the effect of non-invasive ventilation (nIPPV) , (nCPAP), and nasal high flow cannula (NHFC) as a primary mode of ventilation in preterm neonates \<37 gestational week with moderate to severe RD using LUS as regard: I. Primary outcomes: Duration of non-Invasive ventilation. II. Secondary outcomes: Evaluation LUS over the 1 st 7 days of life or weaning from ventilation. Need for intubation and invasive ventilation. Duration of respiratory support. Need for surfactant. Oxygen saturation index and oxygen index. Broncho-pulmonary dysplasia; grade. Duration of hospital stay
Age
0 - 0 years
Sex
ALL
Healthy Volunteers
Yes
Alexandria university, Elshattbi hospital
Alexandria, Egypt
Start Date
November 20, 2024
Primary Completion Date
May 28, 2025
Completion Date
November 1, 2025
Last Updated
February 4, 2025
30
ESTIMATED participants
Nasal humidified heated high flow cannula (NHHHC)
DEVICE
Nasal intermittent positive pressure ventilation (NIPPV)
DEVICE
Nasal continuous positive airway pressure NCPAP
DEVICE
lung ultrasound
DEVICE
Lead Sponsor
Alexandria University
NCT06315556
NCT07061366
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