SakuraBead Used as Resorbable Embolic for Genicular Artery Embolization

Exclusion Criteria

• •1. Severe knee OA (Kellgren-Lawrence grade 4), or
• •2. Current infection of target joint, or
• •3. Life expectancy less than 36 months, or
• •4. Known advanced atherosclerosis as defined by history of lower extremity or pelvis arterial bypass graft, lower extremity or pelvis arterial stent placement or prior history of vascular claudication, or
• •5. Rheumatoid or known serologic diagnosis of autoimmune arthritis, or
• •6. Prior knee replacement surgery in the target knee, or
• •7. Pain score of \>3 NRS on the non-target knee, or
• •8. An acute internal derangement of the target knee, or
• •9. History of uncorrectable coagulopathy, or
• •10. Prior iodinated contrast reaction resulting in anaphylaxis, or
• •11. Active pregnancy as demonstrated by urine or serum β-hCG, or lactating female, or planning pregnancy in the following 12 months, or
• •12. Has undergone an invasive treatment (including but not limited to: corticosteroid injection, hyaluronic acid injections, nerve ablation) in the target knee within the past 3 months, or
• •13. Contraindication to MRI, or
• •14. At the discretion of the Principal Investigator