Allison C Sylvetsky, PhD

CONTACT

Lead Sponsor

George Washington University

Collaborators

Children's Hospital Los Angeles
Children's National Research Institute
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Age

18 - 45 years

Sex

FEMALE

Healthy Volunteers

Yes

•Pregnant
•≤ 16 weeks gestation
•Singleton pregnancy
•Report frequent NNS beverage consumption (≥ 7 servings/week)
•18-45 years of age
•Able to read English at a 5th grade level; and
•Intend to breastfeed for at least the first 6 months of life.
•For infants: The mother must be enrolled and provide assent for the infant to participate.

•Physical or mental concerns preventing study participation;
•Medication (e.g., metformin; GLP-1 agonists) use that may affect body weight, body composition, insulin resistance, or lipid profiles;
•Tobacco or drug use during pregnancy;
•Alcohol consumption (\>1 drink per week) during pregnancy;
•Pre-existing gastrointestinal, inflammatory, or malabsorptive disorders (e.g., - Crohn's disease, ulcerative colitis, inflammatory bowel disease) that may impact NNS absorption or gut microbiota;
•Known suspected/confirmed genetic fetal abnormalities or suspected or known congenital birth defects.
•History of prior gastric bypass surgery.