Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
BeiGene
With
Quotient Sciences
Age
18–55
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Able to understand and sign a written informed consent
Able and willing to comply with all study requirements
Healthy males or healthy females of non-childbearing potential
Agrees to use an adequate method of contraception
Body mass index (BMI) of 18.0 to 32.0 kg/m\^2 as measured at screening or, if outside the range, considered not clinically significant by the investigator.
You may not be if
Positive hepatitis B surface antigen (HBsAg), hepatitis C virus antibody (HCV Ab), or human immunodeficiency (HIV) antibody results
Prior treatment with sonrotoclax
Evidence of renal impairment at screening
Any contraindication to the use of phenytoin (Part A) or itraconazole (Part B)
Current smokers and those who have smoked within the last 12 months
Current users of e-cigarettes and nicotine replacement products and those who have used these products within the last 12 months
History of any drug or alcohol abuse in the past 2 years
Serious adverse reaction or serious hypersensitivity to any drug or formulation excipients
History of clinically significant disorders as judged by the investigator
