A Study of Duvelisib Versus Gemcitabine or Bendamustine in Participants With Relapsed/Refractory Nodal T Cell Lymphoma With T Follicular Helper (TFH) Phenotype
Pathologically confirmed nodal T cell lymphoma with TFH phenotype according to the criteria of the World Health Organization classification (Swerdlow 2017, Alaggio 2022) including any one of Angioimmunoblastic T cell lymphoma (AITL), follicular T cell lymphoma, and other nodal peripheral T cell lymphoma (PTCL) with a TFH phenotype.
Relapsed or refractory to at least 1 prior systemic, cytotoxic therapy for T cell lymphoma.
Measurable disease as defined by Lugano 2014 criteria (Cheson 2014) for T cell lymphoma.
You may not be if
Cutaneous-only disease.
Received prior allogeneic transplant any time in the past or received autologous transplant within 60 days prior to the first dose of study drug.
Received prior treatment with a phosphoinositide-3-kinase (PI3K) inhibitor.
Prior exposure to planned study treatment investigator's choice therapy (gemcitabine or bendamustine) within 60 days prior to the first dose of study drug.
Other protocol-defined criteria apply.
Clareo Health | A Study of Duvelisib Versus Gemcitabine or Bendamustine in Participants With Relapsed/Refractory Nodal T Cell Lymphoma With T Follicular Helper (TFH) Phenotype
