Investigating Myosteatosis in Steatotic Liver Diseases

Exclusion Criteria

• •Liver disease from other causes (alcohol, active viral chronic hepatitis B or C, Wilson\'s disease, autoimmune hepatitis, alpha1-anti-trypsin deficiency,...)
• •Heavy consumption of alcoholic beverages, i.e. \> 140 g or 210 g of ethanol in women or men respectively).
• •Intravenous drug use
• •HbA1C \> 10%
• •Decompensated cirrhosis (presence of ascites, bilirubin level \> 1.2 mg/dL in a patient without Gilbert's syndrome, albumin level \< 35 g/L)
• •Pregnancy
• •Use of drugs that may cause steatosis (methotrexate, amiodarone, tamoxifen, oral corticosteroids) currently or in the last 3 months
• •Change in treatment of hyperglycaemia (dose or medication) in the last 3 months
• •Change in body weight \>5% in the last 3 months
• •Active cancer
• •End stage renal disease or dialysis
• •Type 1 diabetes or secondary diabetes
• •Digestive malabsorption
• •Untreated thyroid disease
• •Taking a treatment under study or approved for NASH (semaglutide, lanifibranor, obeticholic acid).
• •Musculoskeletal disorders, neuromuscular or inflammatory diseases such as connective tissue diseases, myositis and vasculitis that have musculoskeletal manifestations.