Time-restricted Eating and Cognition

Exclusion Criteria

• •weight change \>5% of body weight during the last 3 months
• •pregnancy or breastfeeding
• •allergies (inclusion possible after consultation with study doctor)
• •history of cardiovascular disease (myocardial infarction, stroke, hypertension, hypotension) in the last year
• •severe psychiatric condition, including drug addiction and depression
• •impaired renal or liver function
• •dementia or other severely debilitating cognitive disease
• •history of or current eating disorders (e.g., Bulimia nervosa, Anorexia nervosa, Orthorexia nervosa, Binge-Eating disorder)
• •chronic diseases (e.g., Morbus Crohn, Colitis Ulcerosa)
• •metabolic disorders (e.g., metabolic syndrome, diabetes type 1 or 2)
• •hormonal imbalances (e.g., thyroid gland diseases)
• •consuming diseases (e.g., cancer, kachexie) in the last 2 years
• •surgical removal (partial removal) of the digestive organs (e.g., gastrectomy) or history of bariatric surgery
• •Autoimmune conditions or current infection
• •Blood clotting disorders (e.g., haemophilia)
• •Severe anemia
• •severe claustrophobia
• •blood donation four weeks prior to study entry
• •glucocorticoid therapy (oral)
• •anticoagulant medication (inclusion possible if medication can be paused)
• •taking medications that require regular eating
• •any medications or supplements known to affect sleep, circadian rhythms, immune activity or metabolism
• •taking weight loss, lipid or glucose-lowering medications (any medications that affects metabolism) i.e. metformin
• •pacemaker or other electrical implant
• •vaccination during the study course or in the two weeks' prior
• •immunosuppressive premedication
• •currently on a diet/fasting regime (or within 1 month)
• •professional athletes
• •nicotine consumption
• •drug abuse
• •alcohol consumption per week more than 14 beers (0,3l)/ wine (0,125l)/ sparkling wine (0,1l)/Schnaps (4cl)
• •shift work
• •poor sleep quality (PSQI score \> 10 at medical screening)
• •travel across more than one time zone one month before study or during study period
• •non-removable metallic implants
• •fear of blood draw