At enhanced risk of Alzheimer's Disease (defined as family history of AD, 1st degree family member)
Habitually consume suboptimal diets such as typical Western Diet (i.e., high in animal products, refined carbohydrates and processed food)
Able to communicate well in English
You may not be if
Vegan or Vegetarian
Presence of cognitive impairment at the time of recruitment into the study as measured by the Mini Mental Status Exam (MMSE, score 25-30) and Clinical Dementia Rating (CDR, score=0).
Pre-existing psychosis or psychiatric conditions
Currently receiving treatment for dementia
History of alcohol and/or substance abuse/dependence as determined by a positive endorsement on the MINI+/ If the MINI+ is positive for alcohol or drug dependence, or abuse, the participants will be excluded.
Heavy use of tobacco (greater than 1/2 pack per day)
History of cerebrovascular events
Existing allergies to berry fruits
Use of oral/IV antibiotics in the last 3 months. Use of probiotics in the last 1 month.
Recent Changes (last 3 months) in the use of psychoactive medications or other medications that interfere with the measured outcomes.
Frailty, malnutrition, or food allergy/intolerance requiring special diets.
Body weight at enrollment greater than 400lbs due to weight restrictions on the MRI table.
Women who are pregnant, lactating, or postpartum for less than 6months.
Women of childbearing age who are not practicing birth control or are planning to get pregnant during the study.
Unable to safely participate in the MRI (claustrophobia, presence of devices affected by MRI such as pacemakers, neurostimulators, metallic foreign body, etc.)
