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Emergency Stroke Unit for Acute Cerebrovascular Events--A Prospective, Multicenter, Week-wise Randomized, Controlled Trial ( ESU-ACE-B )
To compare the door-to-puncture time of patients with hyperacute ischemic stroke (between 4.5-6 hours after the onset of symptoms) treated in a standard stroke unit adherent to guidelines versus treated in Emergency Stroke Unit (a new stroke unit based on low-field magnetic resonance imaging).
Mechanical thrombectomy is an effective reperfusion therapy for patients with acute ischemic stroke due to large vessel occlusion. Faster door-to-puncture time (DPT) is associated with significantly better clinical outcomes. With the development of low-field magnetic resonance imaging, it is poised to play an increasingly significant role in the early diagnosis and management of acute ischemic stroke. This prospective, multicenter, week-wise randomized controlled trial will compare the door-to-puncture time of patients with hyperacute ischemic stroke (between 4.5-6 hours after the onset of symptoms) managed in a standard stroke unit adherent to guidelines versus managed in Emergency Stroke Unit (a new stroke unit based on low-field magnetic resonance imaging).
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Beijing Tiantan Hospital, Capital Medical University
Beijing, China
Start Date
August 4, 2024
Primary Completion Date
February 1, 2025
Completion Date
April 1, 2025
Last Updated
August 12, 2024
100
ESTIMATED participants
Emergency Stroke Unit based on 0.23-T MRI
COMBINATION_PRODUCT
Standard stroke unit adherent to guidelines
COMBINATION_PRODUCT
Lead Sponsor
Yongjun Wang
NCT06075628
NCT06094478
Data Source & Attribution
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