STereotactic Body Radiotherapy (SBRT) for Oligoprogressive Breast Cancer

Exclusion Criteria

• •1. Requires change in systemic therapy line at the time of OP as determined by medical oncologist;
• •2. Progression on 2nd line or subsequent lines of therapy
• •3. Lacks CT or bone scan Imaging within previous 45 days;
• •4. Progression in \>3 sites in the liver or lung;
• •5. Hormone positive disease on endocrine therapy only at time of enrollment;
• •6. Previous radiotherapy to same site or vicinity preventing definitive SBRT (e.g. within 5 cm);
• •7. Lesions deemed not amenable to SBRT due to large size or location;
• •8. Unacceptable fracture risk according to clinician judgement for bone lesions;
• •9. Brain metastasis or Spinal cord compression;
• •10. History of major radiosensitivity syndrome or contraindications to radiotherapy.