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Exploring the Use of Saliva for the Detection of Group A Streptococcus
This study is being done to evaluate whether saliva can be used to diagnose GAS infection and also to compare different testing methods in the microbiology lab. The saliva sample testing will be compared to the throat swab testing to see if saliva testing works as well. The lab will also try different testing methods to see if a faster type of testing (e.g. molecular testing) works as well as the regular method, which takes 48 hours to get results. This is important because throat swabs can be challenging to collect in some children, and saliva is often much easier and more acceptable by children to collect. This could improve our ability to accurately diagnose and treat GAS infections.
Age
0 - 18 years
Sex
ALL
Healthy Volunteers
No
Monica Caldeira-Kulbakas
Toronto, Ontario, Canada
The Hospital for Sick Children
Toronto, Ontario, Canada
Start Date
June 10, 2024
Primary Completion Date
February 28, 2025
Completion Date
April 30, 2026
Last Updated
November 26, 2025
200
ESTIMATED participants
Saliva collection
DIAGNOSTIC_TEST
Lead Sponsor
The Hospital for Sick Children
Data Source & Attribution
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Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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