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Effect of Deep Neuromuscular Block on the Quality of Recovery After Laparoscopic Hysterectomy
BACKGROUND: Some studies have revealed that deep neuromuscular block (NMB) improve surgical conditions and alleviated postoperative pain compared with moderate NMB. The present study investigated deep NMB could improve the quality of recovery after laparoscopic hysterectomy METHODS: seventy-two women with elective laparoscopic hysterectomy were randomly divided into 2 groups: Patients in group A received low-pressure pneumoperitoneum (LPP), which was set at 8-10 mmHg with deep NMB. Patients in group B received standard-pressure pneumoperitoneum (SPP), which was set at 12-14 mmHg with moderate NMB. Primary outcome was the quality of recovery (QoR-15) at 1 day after sugery. The secondary outcomes included postoperative pain, surgical condition, incidence of shoulder pain, the incidence of rescue analgesic drug use, cumulative dose of analgesics, time of first flatus, post-operative nausea and vomiting, time of tracheal tube removal.
Age
18 - 65 years
Sex
FEMALE
Healthy Volunteers
No
Department of Anqing Munucipal Hospital Anesthesiology
Anqing, Anhui, China
Start Date
June 25, 2024
Primary Completion Date
November 25, 2024
Completion Date
November 25, 2024
Last Updated
June 24, 2024
72
ESTIMATED participants
low-pressure pneumoperitoneum
DEVICE
standard-pressure pneumoperitoneum
DEVICE
Lead Sponsor
Anqing Municipal Hospital
NCT07404579
NCT06409260
NCT05169073
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