Application of FET-PET in Fusion With MRI in the Treatment of Glioblastoma Multiforme [TYR-GLIO]

Inclusion Criteria

• •Single macroscopic tumor focus with the appearance of glioblastoma multiforme on MRI with contrast - contrast-enhancing lesion, completely or with central necrosis, with surrounding edema.
• •No history of cancer in other organs. No suspicious lesions on X-ray of the chest and abdomen (CT with contrast).
• •No clinical suspicion of brain abscess - no meningeal symptoms, signs of neuroinfection, fever, elevated inflammatory parameters.
• •Primary tumor, without neurosurgical, radiotherapy or oncology intervention. Prior tumor biopsy is allowed.
• •Tumor eligible for surgical treatment - craniotomy and tumor resection.
• •Age ≥ 18 years but \< 70 years old.
• •Quality of life assessment: KPS ≥ 70.
• •Informed patient consent to the study and proposed treatment.
• •No allergy to contrast agents used in PET and MRI.
• •No medical contraindications to neurosurgery - craniotomy and resection.