National Institute of Allergy and Infectious Diseases (NIAID)
Age
18–any
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
not currently at risk of a sexually transmitted infection and willing to use other methods, such as condoms, for STI prevention;
if diagnosed with an STI in the past two years and/or a partner was diagnosed with an STI in the past year, is willing to use condoms for STI prevention;
willing to provide hair, blood, and urine samples;
not currently enrolled in other STI prevention studies;
able to speak English
transgender women participants should be currently using estrogen gender affirming hormone therapy with blood estrogen levels demonstrating consistent use
transgender men participants should be currently using testosterone gender affirming hormone therapy with blood testosterone levels demonstrating consistent use
able to provide a hair sample of \~50-100 strands of hair that are non-gray, not bleached, and at least 1cm in length
willing to NOT shave hair or have a very short haircut or apply bleach for the duration of the study
has suitable venous access for consecutive blood draws
You may not be if
any health condition that may interfere with participation or the ability to provide informed consent, including any debilitating or life-threatening conditions;
pregnancy or plans to become pregnant;
liver cirrhosis or fulminant liver disease;
known hypersensitivity reaction to doxycycline.
detectable doxycycline in hair at enrollment.
unable to provide a hair sample of \~50-100 strands of hair that are non-gray, not bleached, and at least 1cm in length
does not have suitable venous access for consecutive blood draws
