Seattle Institute for Biomedical and Clinical Research
With
Patient-Centered Outcomes Research Institute
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
COPD: Defined by presence of airflow obstruction (FEV1/FVC \< 0.70) on post-bronchodilator spirometry
≥10 pack year history of tobacco use
Self-reported clinician diagnosis of OSA (or presence of OSA on research HSAT)
BMI ≥ 25 kg/m2
Symptoms of dyspnea defined by MMRC score of ≥1
You may not be if
Self-report of weight change \>15 lbs. during prior 3 months
Current active weight loss treatment, including: 1) research-based commercial weight loss programs (e.g., Weight Watchers, Jenny Craig, HMR, Omada, TOPS, MOVE!); 2) other weight loss or related behavioral health or wellness programs led by trained personnel (professional or lay) in the local community; 3) prescription weight loss medication within last 3 months; and scheduled bariatric surgery.
Severe illness from any cause
Diagnosis of bulimia or history of purging behavior
Active enrollment in pulmonary rehabilitation
Safety and/or adherence concerns due to severe physical or mental health issues or life expectancy \< 12 months. These include but may not be limited to: unstable cardiac arrhythmias, active or recent (within one month) myocardial infarction, active or recent (within one month) COPD exacerbation, angina not well-controlled with medication, significant musculoskeletal comorbidities or physical infirmities that preclude participation in an exercise program, and the need for supplemental oxygen ≥ 5 lpm at rest or with exertion.
Pregnant, lactating, or planning to become pregnant during the study period
