Finding studies
Finding studies
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Michelle Kuznicki, MD
CONTACT
Jackie Ludwig
CONTACT
Lead
Case Comprehensive Cancer Center
The quality of diet can affect the biology of cancer. For example, evidence implies a high fat/ Western diet may impose adverse events on ovarian cancer outcomes, and the potential that the gut microbiome alterations secondary to dietary changes may impact tumor responsiveness to treatment and outcomes. This study seeks to clarify the effect of dietary intervention on the tumor and gut microbiome and ovarian cancer biology. The objectives of this study include: * Primary: To test the feasibility and safety of IF during neoadjuvant chemotherapy (including effects on body composition) * Secondary: To measure the effects of IF on participant reported outcomes, chemotherapy toxicity and quality of life. * Exploratory: To test the effect of IF on pathologic response, systemic inflammatory and immune responses, microbial diversity and metabolic pathway alterations.
Age
18–any
Sex
FEMALE
Healthy volunteers
Not accepted
