Patient is able to give informed consent to participate in the study. LAR consents will not be utilized for this study
Age Range \>18
You may not be if
Previous lower extremity surgery that in the opinion of the principal investigator or qualified research personnel precludes the participant from safely participating on the study.
BMI \> 40.
Contraindication to receiving vancomycin, cefepime, ancef, or other standard of care pre-operative antibiotic (allergy, medical issue, etc).
Inability to administer the IO infusion.
Patient refusal to participate.
Uncontrolled Diabetes Mellitus type 1 or 2, defined as Hemoglobin A1C \>7.5.
Immunocompromised or immunosuppressed patients (HIV, Hep C, end stage renal disease, dialysis, transplant, chemo/radiation treatment in last 6 months, medications).
Vulnerable populations
Clareo Health | Intraosseous vs. Intravenous Vancomycin Administration in Total Ankle Arthroplasty
