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Effect of Oliceridine on Rebound Pain | Clinical Trials | Clareo Health

RECRUITING

Effect of Oliceridine on Rebound Pain

A Clinical Study on the Effect of Oliceridine（TRV130） on Postoperative Rebound Pain and Early Rehabilitation Exercise After Knee Arthroscopy

NCT06382896•The First Affiliated Hospital of Xiamen University

View on ClinicalTrials.gov

Summary

The purpose of this clinical study was to identify the risk factors for postoperative pain outburst in patients undergoing arthroscopic knee surgery after Oliceridine and nerve block, and to evaluate the effect of oxeridine on early rehabilitation exercise in patients. A total of 320 patients undergoing arthroscopic knee arthroscopy under general anesthesia combined with femoral nerve block were selected to record the time and duration of postoperative pain outbreak, pain degree, age, gender, operation type, previous surgical history and other related risk factors.

Eligibility

Age

18 - 70 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1\. Age 18-70 years old;2. Body mass index (BMI) 18-30kg /m2;3. American Society of Anesthesiologists (ASA) Grade I to II;4. Hospital stay \>24h.

Exclusion Criteria

•1\. Patients who cannot understand the numerical rating scale score and give feedback;2. Known allergy to the drug in the study;3. Infection of puncture site with nerve block;4. Oral analgesics for more than 2 weeks before surgery;5. Long-term use of glucocorticoids;6. Simultaneous surgery on both limbs;7. A psychopath;8. Severe compound trauma;9. Pregnant and lactating women.

Locations (1)

First Affiliated Hospital of Xiamen University

Xiamen, Fujian, China

Key Dates

Start Date

January 1, 2024

Primary Completion Date

December 31, 2025

Completion Date

December 31, 2025

Last Updated

April 25, 2024

Enrollment

320

ESTIMATED participants

Conditions

Rebound PainArthroscopic Knee SurgeryOliceridine

Interventions

No intervention

OTHER

Contacts

Bin Yang, doctor

CONTACT

13859986036 yangbin4332@outlook.com

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COMPLETEDNA

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 25, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Effect of Oliceridine on Rebound Pain

Inclusion Criteria

Exclusion Criteria

Heart Rate Variability as a Predictor of Rebound Pain Following Total Knee Arthroplasty

Regional and Intravenous Dexamethasone in The Prophylaxis of Rebound Pain After Supraclavicular Block in Upper Limb Surgeries

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