Influence of Injectable Platelet Rich Fibrin on Different Orthodontic Tooth Movements During Clear Aligner Therapy

Influence of Injectable Platelet Rich Fibrin on Different Orthodontic Tooth Movements During Clear Aligner Therapy: A Prospective Clinical Investigation

NCT06380946•Al-Azhar University

View on ClinicalTrials.gov

Summary

The aim of this prospective clinical project will be to assess the effect of platelet rich fibrin on the rate of different orthodontic tooth movements during clear aligner therapy.

Detailed Description

The aim of this prospective clinical project will be to assess the effect of platelet rich fibrin on the rate of different orthodontic tooth movements during clear aligner therapy.specifically canine retraction,incisors leveling and alignment,maxillary molar distalization and incisors intrusion

Eligibility

Age

15 - 22 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•1\. Age ranges from 15 to 22 years. 2. Bilateral Class II molar relationship. 3. Skeletal Class I or mild Class II relationship. 4. Normal or decreased vertical height. 5. No posterior crowding or spaces. 6. Fully erupted maxillary first and second molars. 7. Congenitally missing or extracted third molars. 8. Good oral hygiene. 9. Absence of any periodontal disease and alveolar bone loss. 10. Absence of medications that may inhibit orthodontic movement
•initial bonding appointment; 6. No required management with interproximal stripping, inter-maxillary elastics, open NiTi springs, and removable or extra-oral devices. Canine retraction Eligibility criteria
•Age, 15 to 25 years; Class ii division 1 malocclusion with mild or no crowding; No previous orthodontic treatment; No systemic disease that might have affected bone formation or density, such as osteoporosis, hyperparathyroidism, or vitamin d deficiency; Adequate oral hygiene; Probing depth values not exceeding 3 mm across the Entire dentition; Adequate thickness of the attached gingiva (1-2 mm); No radiographic evidence of bone loss

Exclusion Criteria

•\-

Locations (1)

AlAzhar university

Cairo, Egypt

Key Dates

Start Date

June 1, 2024

Primary Completion Date

October 1, 2024

Completion Date

November 1, 2024

Last Updated

April 24, 2024

Enrollment

ESTIMATED participants

Conditions

Effect of Platelet Rich FibrinDuring Clear Aligner Therapy

Interventions

iPRF

BIOLOGICAL