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COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease | Clinical Trials | Clareo Health

RECRUITINGNA

COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease

NCT06380075•University of Wisconsin, Madison

View on ClinicalTrials.gov

Summary

The goal of this research study is to compare two ultrawide field cameras to the gold standard imaging system to evaluate the back of the eye. The main question it aims to answer is the same results and information can be acquired from all of the cameras for evaluating and monitoring inherited retinal diseases (IRDs). Participants will: * undergo pupillary dilation * have photographs taken of the inside of the eyes using three different cameras

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Participants 18 years and older with a clinical and/ or genetic diagnosis of IRD recruited either from the clinic and/or the Inherited Ocular Disease Registry to participate in this trial
•Participants that are willing to participate as evidenced by signing the written informed consent

Exclusion Criteria

•Presence of ocular conditions other than an IRD which may affect the quality of ocular imaging including but not limited to advanced cataracts, corneal disorders, nystagmus, vitreous hemorrhage, or poor dilation
•Presence of ocular conditions other than an IRD which may affect interpretation of retinal imagining including but not limited to epiretinal membrane, choroidal neovascular membrane, or macular scarring
•Patients with advanced IRDs who are unable to fixate for imaging
•Patients unable to tolerate ocular imaging
•Patients who do not wish to participate

Locations (1)

Department of Ophthalmology and Visual Sciences

Madison, Wisconsin, United States

Key Dates

Start Date

August 29, 2024

Primary Completion Date

December 1, 2026

Completion Date

December 1, 2026

Last Updated

December 26, 2025

Enrollment

ESTIMATED participants

Conditions

Retinal Disease

Interventions

Spectralis FAF imaging

DEVICE

Optos imaging

DEVICE

Clarus imaging

DEVICE

Contacts

Angie Adler

CONTACT

608-265-7557 amadler1@wisc.edu

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 26, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease

Inclusion Criteria

Exclusion Criteria

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