Radicle GI Health 24: A Study of Health and Wellness Products on GI Health and Related Health Outcomes

Exclusion Criteria

• •Report being pregnant, trying to become pregnant, or breastfeeding
• •Unable to provide a valid US shipping address and mobile phone number
• •Reports current enrollment in another clinical trial
• •Reports being a heavy drinker (defined as drinking 3 or more alcoholic beverages per day)
• •Unable to read and understand English
• •Reports a current and/or recent (up to 3 months ago) major illness and/or surgery that poses a known, significant safety risk.
• •Reports a diagnosis of cardiac dysfunction, liver or kidney disease that presents a known contraindication and/or a significant safety risk with any of the study product ingredients. NYHA (New York Heart Association) Class Ill or IV congestive heart failure, atrial fibrillation, uncontrolled arrhythmias, cirrhosis, end-stage liver disease, stage 3b or 4 chronic kidney disease, or kidney failure
• •Reports taking medications that have a well-established moderate or severe interaction, posing a substantial safety risk with any of the study product ingredients. Anticoagulants, antihypertensives, anxiolytics, antidepressants, chemotherapy, immunotherapy, sedative hypnotics, seizure medications, medications that warn against grapefruit consumption, corticosteroids at doses greater than 5 mg per day, diabetic medications, oral anti-infectives (antibiotics, antifungals, antivirals) to treat an acute infection, antipsychotics, MAOls (monoamine oxidase inhibitors), or thyroid products
• •Reports current use of the primary ingredient(s) and/or similar product(s) to the active study product(s) that may limit the effects of the study product
• •Lack of reliable daily access to the internet