Loading clinical trials...

Abundance of a Natural Odour in Human Cerebrospinal Fluid After Olfactory Exposure | Clinical Trials | Clareo Health

NOT_YET_RECRUITINGEARLY_PHASE1

Abundance of a Natural Odour in Human Cerebrospinal Fluid After Olfactory Exposure

Abundance of a Natural Odour in Human Cerebrospinal Fluid After Olfactory Exposure - the OLFO-Brain Study

NCT06370845•University Hospital, Basel, Switzerland

Summary

The goal of this clinical trial is to investigate the abundance of a natural odour in human cerebrospinal fluid in obese and lean participants after inhalation thereof. Participants will undergo blood sample collection and inhalation of either a natural odour or placebo through an inhaler in addition to a liquor puncture prescribed in standard of care context.

Eligibility

Age

18 - 60 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Age 18-60 years
•Written informed consent
•Scheduled for routine liquor puncture
•BMI ≥ 30 kg/m2
•No proven diagnose of diabetes
•Age 18-60 years
•Written informed consent
•Scheduled for routine liquor puncture
•BMI 18-25 kg/m2

Exclusion Criteria

•Known allergy to the natural odour
•Acute upper respiratory tract infection, acute or chronic sinusitis
•Present or past surgical intervention of the nasal cavity, the paranasal sinus, the pituitary or the frontal brain
•Pregnancy/lactation
•Any kind of severe chronic disease (e.g. severe heart failure, active cancer disease, severe renal impairment with an estimated glomerular filtration rate \<30 ml/min/m2)
•Inability to understand the study procedure and to sign the study consent

Locations (1)

University Hospital Basel

Basel, Switzerland

Key Dates

Start Date

May 1, 2024

Primary Completion Date

August 31, 2024

Completion Date

October 30, 2024

Last Updated

April 17, 2024

Enrollment

ESTIMATED participants

Conditions

Overweight and Obesity

Interventions

Inhalation - Natural Odour

COMBINATION_PRODUCT

Inhalation - Placebo

COMBINATION_PRODUCT

Contacts

Katharina Timper, Prof. Dr. med.

CONTACT

0041 61 328 57 42 katharina.timper@usb.ch

Isabel M Hofer

CONTACT

0041 61 328 68 14 Isabelmarie.hofer@usb.ch

Nutrition Care in Patients Living With Chronic Pain

NCT06277232

Nutrition PoorOverweight and Obesity+2 more

View study

RECRUITINGNA

The Effects of a 4-week Supplementation With a Ketogenic Nutrient Mix on 24-hour Substrate Metabolism and Muscle Health

NCT07395973

Overweight and Obesity

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 17, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Abundance of a Natural Odour in Human Cerebrospinal Fluid After Olfactory Exposure

Inclusion Criteria

Exclusion Criteria

Nutrition Care in Patients Living With Chronic Pain

The Effects of a 4-week Supplementation With a Ketogenic Nutrient Mix on 24-hour Substrate Metabolism and Muscle Health

Social Determinants and a Diabetes Prevention Program Tailored for African Americans

Becoming United in Lifestyle Decisions

Effect of GLP1 Receptor Agonist on Brain Insulin Responsiveness

Protein Digestion After Bariatric Surgery in Older Adults