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A randomized controlled clinical study was conducted to elucidate the relationship between the lower extremity biomechanics of patients undergoing early gait training after ACLR surgery.The relationship between the biochemical characteristics of cartilage and the biomechanical risk index were proposed to providing exercise guidance and training for ACLR people and it is suggested that it can prevent and reduce the risk of cartilage degeneration early after operation.
In this randomized controlled clinical study, patients with primary unilateral ACL rupture were included. In addition to standardized rehabilitation training content, gait training intervention under weight loss was added to the subjects in the early postoperative period. The control group only received standardized rehabilitation training. Based on motion testing and dynamic analysis, the influence of early postoperative gait training on postoperative gait biomechanical characteristics was explored. And the influence of early cartilage health status; Based on functional MRI, the effects of early postoperative gait training on biochemical parameters of knee tibiofemoral and patellofemoral cartilage were investigated.
Age
18 - 40 years
Sex
ALL
Healthy Volunteers
No
Peking University Third Hospital
Beijing, China
Start Date
July 22, 2024
Primary Completion Date
December 31, 2027
Completion Date
December 31, 2027
Last Updated
July 25, 2025
60
ESTIMATED participants
lower-body positive-pressure
OTHER
Lead Sponsor
Peking University Third Hospital
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