Age

18–any

Sex

ALL

Healthy volunteers

Not accepted

Hyperkaliemia (plasma potassium \> 5.5 mmol/L) at baseline or at the start of potassium enriched diet
Use of potassium binders at baseline or at the start of potassium enriched diet
Use of dual RAAS-blockade, mineralocorticoid receptor blockers or potassium-sparing diuretics
Use of calcineurin inhibitors
Use of trimethoprim and sulfamethoxazole
Patients with a previous history of ventricular cardiac arrhythmia
Patients with a prolonged QTc time on ECG
Kidney transplantation patients
Patients with a life expectancy of \< 6 months
Incapacitated subjects or subjects who are deemed unfit to adequately adhere to instructions from the research team
Women who are pregnant, breastfeeding or considering pregnancy in the coming 6 months.
Hypersensitivity to SCZ

Sodium Zirconium Cyclosilicate to Allow Liberal Fruit and Vegetable Intake for Patients With CKD Stage 3b and 4