Omalizumab in Severe Asthmatics With Food Allergy

Children (6-18 yrs) with severe asthma eligible for treatment with Omalizumab and reporting food anaphylaxis to be assessed for their concomitant food allergy. At T0: * oral food challenges (OFCs) to establish the threshold of reaction to the culprit food(s); * number and severity of food-allergic reactions in the previous 12 months recorded * Asthma Control Test * Food Allergy-Quality of Life (FA-QoL) questionnaire * total IgE * specific IgE for the culprit foods At T1 - four months after starting Omalizumab treatment: * OFCs to the previously positive foods with evaluation of the threshold of reaction * number and severity of food-allergic reactions in the previous 4 months recorded * Asthma Control Test * Food Allergy-Quality of Life (FA-QoL) questionnaire * total IgE * specific IgE for the culprit foods At T2 - eight months after starting Omalizumab treatment: * OFCs to the previously positive foods with evaluation of the threshold of reaction * number and severity of food-allergic reactions in the previous 4 months recorded * Asthma Control Test * Food Allergy-Quality of Life (FA-QoL) questionnaire * total IgE * specific IgE for the culprit foods At T1 - twelve months after starting Omalizumab treatment: * OFCs to the previously positive foods with evaluation of the threshold of reaction * number and severity of food-allergic reactions in the previous 4 months recorded * Asthma Control Test * Food Allergy-Quality of Life (FA-QoL) questionnaire * total IgE * specific IgE for the culprit foods