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Risk Factors for Acute Kidney Injury in Patients Undergoing Total Joint Arthroplasty
The authors aimed to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty.
Aim: The primary aim of the current study is to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty. Considering that this patient group is mostly composed of advanced age and comorbid patients, the secondary aim of the study is to identify risky patients with predictable risk factors and to chart a way to make preoperative optimizations of the patients before developing postoperative complications. Materials and Methods: Patients who underwent joint arthroplasty between 2015 and 2020 in Ankara University Faculty of Medicine, Department of Orthopedics and Traumatology were included. Within the scope of the study, patients' gender, age, weight, height, body mass index values, smoking, American Society of Anesthesiologist (ASA) score, Charlson-Comorbidity Index score (CCI), type of operation, duration of surgery, presence of intraoperative hypotension, anesthesia method , diabetes, hypertension, coronary artery disease, presence of congestive heart failure, presence of preoperative anemia, preoperative uric acid and albumin level, use of nephrotoxic agents in the perioperative period, basal creatinine and glomerular filtration rate (GFR) values, platelet suspension in the perioperative period, erythrocyte suspension, Amounts of fresh frozen plasma transfusions, postoperative creatinine at 24 hours - 48 hours - discharge, GFR values and Kidney Disesae Improving Global Outcomes (KDIGO) scores, length of hospital stay and length of stay in the intensive care unit were evaluated.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Ankara University Medical School Anesthesiology and ICU Department
Ankara, Turkey (Türkiye)
Start Date
June 1, 2022
Primary Completion Date
December 31, 2022
Completion Date
December 31, 2022
Last Updated
March 6, 2024
911
ACTUAL participants
acute kidney injury
OTHER
Lead Sponsor
Ankara University
NCT07225751
NCT06143306
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT04848896