High preoperative suspicion (or diagnosis) of advanced primary epithelial ovarian, fallopian tube, or primary peritoneal carcinoma (stage IIIC or IV), as determined by CT or MRI of the abdomen/pelvis
Planned for exploratory laparotomy and primary or interval cytoreductive surgery
Preoperative hemoglobin concentration ≥10 mg/dl within 45 days of surgery
Patients scheduled for cytoreductive surgery, with or without other planned procedures o Note: Patients scheduled for only diagnostic laparoscopy should not be included
A history of cerebrovascular disease
A history of congestive heart failure
A history of uncontrolled hypertension
A history of restrictive or obstructive pulmonary disease
A history of renal dysfunction (Cr \>1.6 mg/dl)
Abnormal coagulation parameters (INR \>1.5 not on coumadin, or platelet count \<100,000 mcL)
Presence of active infection
Evidence of hepatic metabolic disorder (bilirubin \>2 mg/dl, ALT \>75 U/L in the absence of biliary tract obstruction)
Preoperative autologous blood donation within last 30 days or plan to donate autologous blood prior to surgery
Refusal to accept allogenic or autologous blood transfusion
Patients scheduled for cytoreductive surgery with planned Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
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A history of active coronary artery disease
Clareo Health | Study of Acute Normovolemic Hemodilution (ANH) in People With Ovarian Cancer Who Are Having Cytoreductive Surgery
