Microwave Ablation in the Treatment of Early-stage Unifocal Invasive Breast Cancer

Exclusion Criteria

• •1. multicentric or multifocal breast tumor;
• •2. the tumor located on nipple and areola area;
• •3. signs of extensive intraductal carcinoma on imaging examination (diffuse malignant calcification on breast X-ray or segmental distribution, non-mass enhancement, ductal or linear enhancement \> 2.5 cm on MRI);
• •4. extensive intraductal component in invasive cancer (more than 50% of the tumor volume) confirmed by pathology;
• •5. invasive lobular carcinoma, metaplastic carcinoma or carcinoma with sclerosing adenosis;
• •6. patients who were pregnant or breastfeeding;
• •7. patients with evidence of coagulopathy, chronic liver diseases or renal failure;
• •8. patients with previous treatment including chemotherapy, targeted drug therapy, or local radiation therapy, etc;
• •9. patients with substance abuse, or mental or psychological disorders that may interfere with study compliance;
• •10. any condition that is unstable or likely to compromise the patient's safety and compliance;
• •11. patients enrolled in other clinical trials;
• •12. diseases or symptoms that other investigators consider unsuitable for participation.