A Comparative Study of Using Scorpion Antivenom Versus Scorpion Antivenom and Prazosin

Tools of the study: 1. Dose and administration of prazosin: 30 μg/kg/dose of prazosin will be delivered orally every 6 hours 4 doses, in adults we shouldn't exceed 1 mg per dose. Prazosin will be delivered using a nasogastric tube while securing the patient's airway in the event of vomiting or unconsciousness. Every 30 minutes for the first three hours, every hour for the following six, and then every four hours until improvement, blood pressure, pulse rate, respiration rate, and oxygen saturation will be measured. When pain is the only symptom, prophylaxis shouldn't be given. To avoid the first-dose phenomenon, the patient should remain in a laying position for around 3 hours (even while the case is being examined) (Shoreit et al., 2019). Dose of antivenom 1-1 ampoule intramuscular and/ or, 2-1 to 5 Polyvalent anti-scorpion serum ampoules produced by the vaccine \& serum institution (VACSERA)in Egypt according to the severity of the case on 200 to 500 ml glucose 5% infusion and assess the patient clinically to repeat the dose after 4 to 6 hours. (Shoreit et al., 2019) 2. A prepared sheet containing 1. the demographic characteristics of each patient 2. Vital signs and degree of coma at time of admission of the patient. 3. First aid management as resuscitation. 4. Supportive management will be done to the patients during the admission will be recorded. 5. Cardiac enzymes measurements, duration of hospital stay and the outcome of patients in each group.