The Predictive Biomarkers in Patients With Locally Advanced Non-small Cell Lung Cancer

Exclusion Criteria

• •1. Pathologic type was adenocarcinoma with EGFR gene mutation or ALK gene rearrangement.
• •2. Patients with other active malignancies within 5 years or at the same time.
• •3. Active or previously documented autoimmune or inflammatory diseases (including inflammatory bowel disease, diverticulitis \[except diverticular disease\], systemic lupus erythematosus, Sarcoidosis syndrome, Wegener' s syndrome).
• •4. History of allogeneic organ transplantation.
• •5. History of active primary immunodeficiency.
• •6. Patients with uncontrolled concurrent diseases, including but not limited to persistent or active infection (including tuberculosis, hepatitis B, hepatitis C, human immunodeficiency virus, etc.), symptomatic congestive heart failure, uncontrolled hypertension, unstable angina pectoris, uncontrolled arrhythmia, active interstitial lung disease, severe chronic gastrointestinal disease with diarrhea or mental illness.
• •7. Women of child-bearing potential who are pregnant or breastfeeding.
• •8. The investigator judged other situations not suitable for inclusion in this study.