Accommodation Response in Hypermetropic Anisometropia (ARIHA Study)

Inclusion Criteria

• •Phase 1
• •4-10 years (at recruitment)
• •Have hypermetropic anisometropia with ≥1.00D of difference (in spherical equivalent)
• •Are currently undergoing treatment for hypermetropic anisometropia (including refractive adaptation and/or occlusion treatment - patching or atropine)
• •Visual acuity in non-amblyopic eye ≤0.200 logMAR
• •Any level of VA in amblyopic eye (worse than non-amblyopic eye)
• •No manifest strabismus
• •Accept microT with/without identity
• •No other eye conditions as cause of amblyopia (e.g. stimulus deprivation amblyopia/strabismic amblyopia)
• •No significant health conditions that would impact vision or accommodation response (e.g. Down's Syndrome/Cerebral Palsy)
• •Informed consent from parent / guardian and assent from child (over 5 years)
• •Phase 2
• •4-10 years (at recruitment)
• •Hypermetropic anisometropic amblyopes ≥1.00D of difference (in spherical equivalent)
• •Finished standard amblyopia occlusion treatment (including patching and/or atropine)
• •Asymmetric accommodation responses (Anti-A and Aniso-A) following preliminary assessment
• •VA in non-amblyopic eye ≤0.200 logMAR
• •Residual amblyopia (defined as interocular difference of ≥0.2 log units)
• •No manifest strabismus
• •Accept microT with/without identity
• •No other eye conditions as cause of amblyopia (e.g. stimulus deprivation amblyopia/strabismic amblyopia)
• •No significant health conditions that would impact vision or accommodation response (e.g. Down's Syndrome/Cerebral Palsy)
• •Informed consent from parent / guardian and assent from child (over 5 years)