Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
AskBio Inc
With
Bayer
Age
45–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age
1. Male and female adults 45-75 years of age inclusive, at the time of signing of informed consent Type of Subject and Disease Characteristics
2. Diagnosed with Parkinson's disease in the past 4-10 years (inclusive) as defined by the following:
1. Presence of bradykinesia PLUS any of the following:
* Rigidity
* Rest tremor
* Postural instability
2. Presence of motor fluctuations as measured by the PD Motor Diary
3. Stable anti-parkinsonian medication regimen for \>/= 4 weeks prior to screening
4. Must demonstrate responsiveness to levodopa therapy
You may not be if
Known history or current evidence of medical, genetic, or neurological conditions that may provide an alternative to idiopathic PD diagnosis
Presence or history of significant vascular and/or cardiovascular disease
Presence of significant cognitive impairment, poorly controlled depression/anxiety
Presence or history of psychosis or impulse control disorder
History of malignancy other than treated cutaneous squamous or basal cell carcinomas
Presence of clinically relevant conditions that could compromise surgical suitability and/or subject safety
Contraindication to magnetic resonance imaging and/or use gadolinium-based contrast agents
Prior history of brain surgery including, but no limited: DBS, pallidotomy focused ultrasound thalamotomy, or other experimental neurosurgical procedure
