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Vitamin D & Levothyroxine Combination Versus Levothyroxine on Lipid Profile in Hypothyroidism | Clinical Trials | Clareo Health

COMPLETEDPHASE3

Vitamin D & Levothyroxine Combination Versus Levothyroxine on Lipid Profile in Hypothyroidism

To Compare the Effectiveness of Vitamin D & Levothyroxine Combination Therapy and Levothyroxine Alone on Serum Lipid Profile in Patients With Hypothyroidism

NCT06276205•King Edward Medical University

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to study the improvement of lipid levels in hypothyroid individuals after staring treatment. The main question it aims to answer is: • whether adding Vitamin D to standard therapy has any additional benefits Participants will be given Vitamin D in replacement doses according to their pre-existing Vitamin D level in addition to levothyroxine. Researchers will compare them with another group receiving only levothyroxine to see how much lipids improve in them

Eligibility

Age

12 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patients of all genders.
•Age more than 12 years
•Biochemically hypothyroid (overt \& subclinical)
•Vitamin D level between 10-70ng/ml
•TC \<250mg/dl, LDL 70-144mg/dl, TGs 150-499mg/dl

Exclusion Criteria

•Known Atherosclerotic Cardiovascular Disease
•BMI\>35kg/m2
•History of Alcoholism (\>14 units/day)
•History of Beta blocker intake
•Patient taking lipid lowering drugs

Locations (1)

King Edward Medical University

Lahore, Punjab Province, Pakistan

Key Dates

Start Date

March 1, 2024

Primary Completion Date

January 1, 2025

Completion Date

January 1, 2025

Last Updated

March 11, 2025

Enrollment

ACTUAL participants

Conditions

Hypothyroidism PrimaryLipid DisorderDyslipidemias

Interventions

Vitamin D

DRUG

Levothyroxin

DRUG

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Hypothyroidism Primary

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 11, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Vitamin D & Levothyroxine Combination Versus Levothyroxine on Lipid Profile in Hypothyroidism

Inclusion Criteria

Exclusion Criteria

Physical Activity, Fatigue, Social Support, and Psychological Well-Being in Women With Primary Hypothyroidism

A Study on Efficacy and Safety of HST101 in Chinese Patients with Hypercholesterolemia

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Dietary Supplementation on Body Fat Composition