Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Oncology Institute of Vojvodina
With
University of Bern
The following erythrocyte indices based on the preoperative complete blood count results will be calculated for each patient one day prior to surgical treatment:
* Mentzer index: MCV / RBC
* Green and King index: MCV2 x RDW / (100 x HGB)
* RDW index: MCV x RDW / RBC
* Shine and Lal index: MCV2 x MCH / 100
* England and Fraser index: MCV - RBC - (5 x HGB) - 3.4
* Srivastava index: MCH / RBC
* Ricerca index: RDW / RBC
* Ehsani index: MCV - (10 x RBC)
* Sirdah index: MCV - RBC - (3 x HGB)
* Sehgal index: MCV2 / RBC
The Ganzoni equation for calculating total iron deficit will be calculated for each patient one day prior to surgical treatment, using the following formula:
total iron deficit \[mg\] = body weight \[kg\] x (target hemoglobin \[g/L\] - actual hemoglobin \[g/L\]) x 2.4 + iron depot \[mg\]
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Adult patients (˃ 18 years of age)
ASA III clinical status
Patients undergoing radical surgical treatment of colorectal cancer
Signed written informed consent
You may not be if
Patients undergoing palliative surgical treatment of colorectal cancer
Anaemic patients without iron deficiency, defined as: normal serum iron concentration, TSAT, TIBC, UIBC, and decreased HGB, HCT and RBC
Presence of other type of anaemia than iron deficiency anaemia (e.g. alpha- or beta-thalassemia, sickle-cell anaemia, etc.)
History of red blood cell transfusion in the period of 120 days prior to hospital-admission
Stage III, IV, or V of chronic kidney disease (creatinine clearance \< 60 mL/min)
Significant intraoperative bleeding, which requires transfusion of red blood cell products, calculated using the Gross-formula:
allowable blood loss \[mL\] = (estimated blood volume \[mL\] x (initial HGB \[g/L\] - HGB level when transfusion is required \[g/L\])) / average of initial HGB and HGB level when transfusion is required \[g/L\] The cut-off value for HGB level when transfusion is required is set to 80 g/L.
Clareo Health | Iron-deficiency Anaemia and Its Impact on Recovery After Colorectal Cancer Surgery
