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Flexible-bronchoscopy Trial for Moderate and Severe Thoracic Trauma Patients Without Brain Injury
The study aims to evaluate the effectiveness of bronchoscopic sputum suction in patients with severe thoracic illness-induced respiratory failure. The study will compare the outcomes of patients who receive bronchoscopic sputum suction versus blind negative pressure aspiration for sputum removal. The study will measure baseline data, postoperative blood gas conditions, and clinical parameters, such as time of invasive ventilation, total time of ventilation, hospital stay, weaning success rate, reintubation rate, ventilator-associated pneumonia incidence, and fatality rate. The study aims to determine whether bronchoscopy-assisted sputum removal is superior to blind negative pressure aspiration in improving patient outcomes.
The aim of the present randomized control trial is to assess the value of bronchoscopic sputum suction in patients with severe thoracic illness-induced respiratory failure. To decrease group differences in baseline characteristics and blood gas conditions, patients will be randomly assigned to receive either bronchoscopy-assisted or negative pressure aspiration for sputum suction, while the remaining treatment course will be the same. The study will measure major clinical indicators such as time of invasive ventilation, total time of ventilation, hospital stay, weaning success rate, reintubation rate, ventilator-associated pneumonia incidence, and fatality rate to provide strong evidence for the efficacy of each suction method.
Age
20 - 99 years
Sex
ALL
Healthy Volunteers
No
Department of Traumatology, National Taiwain University Hospital
Taipei, Taiwan
NTUH Hsin-Chu Branch; NTUH Yun-Lin Branch
Taipei, Taiwan
Start Date
December 1, 2024
Primary Completion Date
December 31, 2025
Completion Date
December 31, 2025
Last Updated
February 20, 2024
60
ESTIMATED participants
bronchoscopic sputum suction
PROCEDURE
negative pressure aspiration suction
PROCEDURE
Lead Sponsor
National Taiwan University Hospital
Data Source & Attribution
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Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT05692076