Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of British Columbia
With
Focused Ultrasound Foundation
Age
40–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Confirmed diagnosis of Parkinson's disease
Resting tremor score (MDS-UPDRS III 3.17 Rest Tremore Amplitude (RUE or LUE)) ≥ 2
Between the ages of 40-80 years
Hoehn and Yahr stage between 1-3 (mild to moderate PD) in the "ON" state
Patients who are willing to have a partial (\~8 cm diameter circular area above the ear) hair shaving.
You may not be if
Atypical Parkinsonism
History of essential tremor
Dementia preventing informed consent
Change in Parkinson's medication with the last 2 weeks
Neurological disease other than PD, including Alzheimer's disease, multi-infarct dementia, Huntington's disease, normal pressure hydrocephalus, a brain tumor, progressive supranuclear palsy, seizure disorder, subdural hematoma, multiple sclerosis, or history of significant head trauma
Unstable medical conditions or serious disease/conditions (e.g., cancer undergoing active treatment, poorly controlled diabetes)
Concurrent treatment for PD with Duodopa
Concurrent treatment for PD with deep brain stimulation (DBS)
Thickness of the temporal bone \< 7 mm
Individuals should also not participate if they have any of the following contraindications for undergoing fMRI scanning:
Cardiac pacemaker, wires, or defibrillator
Metal in eye or orbit, including the history of any eye injury involving metal fragments and increased risk due to (history of) working as a metal worker (grinding, machining, or welding)
