Novel Approaches to Assessing Cannabis Impaired Driving (NAACID)

Exclusion Criteria

• •1. Prisoners
• •2. Participants who have nocturnal schedules (e.g., work night shifts)
• •3. Participants with a history of abuse or addiction to substances other than cannabis (e.g., prescription and non-prescription pharmaceuticals, alcohol, or illicit drugs)
• •4. Participants who have expressed an interest in substance abuse treatment within the 60 days prior to study enrollment
• •5. Participants who report consuming an average of \>3 alcoholic drinks per day in the 30 days prior to study enrollment
• •6. Participants with any past or current diagnosis of schizophrenia, narcolepsy, heart disease, epilepsy, or a traumatic brain injury
• •7. Participants who are currently experiencing untreated bipolar disorder, major depression, sleep apnea, or other uncontrolled medical conditions as determined by the investigators (e.g., hypertension)
• •8. Participants with a known balance or gait disorder
• •9. Participants with color blindness (Phase 2 only)
• •10. Participants who currently wear hard contact lenses for vision correction (Phase 2 only)
• •11. Participants who have donated 450 mL or more of blood in the two weeks prior to study enrollment
• •12. Participants who are pregnant or breastfeeding (female participants only)
• •13. Participants who report never using cannabis before in their lifetime (Phases 1 \& 2 only)
• •14. Participants with a history of clinically significant adverse event(s) associated with cannabis intoxication (e.g., lightheadedness, nausea, dizziness, etc., cannabis use groups only)
• •15. Participants with uncorrected visual acuity disorder, defined as binocular vision worse than 20/40 (Phases 2, 3 \& 4 only; determined at screening)
• •16. Participants with a body mass index \>40 kg/m2 (determined at screening)
• •17. Participants with a positive breath alcohol test (breathalyzer) at screening
• •18. Participants who are otherwise unsuitable for inclusion in the study, based on the opinion of the investigator