The Effect of Lactobacillus Delbrueckii Subsp. Bulgaricus on Human's Weight Reduction

Exclusion Criteria

• •History of diabetic ketoacidosis
• •Medical records indicating the occurrence of cerebrovascular disease, acute myocardial infarction, coronary artery bypass surgery, placement of coronary artery stents, or peripheral vascular disease within the last 6 months
• •Occurrence of acute infectious diseases within the last month and antibiotic use for \> 7 days
• •Short-term use of steroids, NSAIDs, immunosuppressive drugs, interferons, immunomodulators, or any changes in the dose of long-term medications within the last month
• •Use of any weight-loss drugs in the last three months (including Orlistat, Lorcaserin, and liraglutide)
• •History of any cancer or undergoing cancer treatment in the past 5 years
• •Abnormal liver function (GOT or GPT greater than 3 times the normal upper limit) or liver cirrhosis
• •Impaired kidney function (eGFR \< 30 mL/min/1.73 m2)
• •History of alcohol abuse
• •Participation in any other interventional clinical research within the last month
• •Pregnant and breastfeeding women
• •History of allergy to the investigational product
• •Participants deemed unsuitable for inclusion by the principal investigator