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Effect of Aloe Vera Gel as an Intra Canal Medicament in Patients With Asymptomatic Periapical Lesions.
This research will overview the effect of aloe vera gel (AVG) as intra canal medicament in patients with asymptomatic periapical lesions. It will provide endodontists with scientific evidence regarding the beneficial use of AVG as an intracanal medicament owing to its superior antibacterial and analgesic properties as compared to routinely used commercial intra canal medicaments.
Objective: To evaluate the effect of aloe vera gel based on clinical signs and symptoms as an intracanal medicament in asymptomatic periapical lesions over a period of three weeks. Methodology: Fresh AVG will be prepared. It will be placed as intracanal medicament after cleaning and shaping in patients with asymptomatic periapical lesions in group A while in group B (control group) no intracanal medicament will be placed. Patients will be randomly divided into two groups by randomization in Statistical Package for Social Sciences software (SPSS v24.0). They will be recalled for one week and three week follow ups and in case of no clinical signs and symptoms endodontic procedure will be completed. Statistical analysis: Descriptive statistics will be used for reporting age. Frequencies and percentages will be calculated for categorical variables and intergroup comparison will be done by chi square test
Age
All ages
Sex
ALL
Healthy Volunteers
No
Islamabad Dental Hospital
Islamabad, Federal, Pakistan
Start Date
November 30, 2023
Primary Completion Date
August 20, 2024
Completion Date
November 15, 2024
Last Updated
May 21, 2025
60
ACTUAL participants
Aloe vera Gel
BIOLOGICAL
Lead Sponsor
Islamabad Medical and Dental College
NCT05888935
NCT06643676
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT06739200