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COMPLETEDPHASE4

Erector Spinae Plane Block Vs. IPACK Block with Adductor Canal Block for Total Knee Arthroplasty

NCT06233630•Poznan University of Medical Sciences

Summary

Effect of Erector Spinae Plane Block and iPACK block with Adductor Canal Block on pain management, and NLR and PLR following knee arthroplasty

Detailed Description

Knee arthroplasty is one of the most common orthopedic procedures, especially in elderly patients, due to the deformation of joints. Patients may complain of severe pain due to surgical trauma and prosthesis. Regional anesthesia methods may be performed to reduce the inflammatory response, opioid consumption, and opioid-related side effects. In recent years, the influence of regional anesthesiology on reducing the inflammatory response after surgical procedures has been emphasized. However, very few studies have evaluated the effect of various methods of anesthesia on the NLR.

Eligibility

Age

18 - 100 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patients with ASA classification I-III,
•Aged 20-100 years,
•scheduled for knee arthroplasty under spinal anaesthesia

Exclusion Criteria

•Patients who have a history of bleeding diathesis,
•Take anticoagulant therapy,
•have a History of chronic pain before surgery,
•have Multiple trauma,
•cannot assess their pain (dementia),
•have been operated on under general anaesthesia,
•have an infection in the area
•do not accept the procedure

Locations (1)

Poznan University of Medical Sciences

Poznan, Poland

Key Dates

Start Date

March 30, 2024

Primary Completion Date

August 16, 2024

Completion Date

August 20, 2024

Last Updated

September 26, 2024

Enrollment

ACTUAL participants

Conditions

Knee OsteoarthritisKnee Pain ChronicKnee Arthritis

Interventions

Control Test - spinal anesthesia

DRUG

Ropivacaine 0.2% Injectable Solution ESPB

DRUG

Ropivacaine 0.2% Injectable Solution iPACK+ACB

DRUG

A Phase Ib Study to Evaluate the Efficacy and Safety of HRS-2129 in Patients With Knee Osteoarthritis

NCT07351968

Moderate Pain in Knee OsteoarthritisSevere Pain in Knee Osteoarthritis

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RECRUITINGNA

General vs Spinal in Total Joint Arthroplasty (TJA)

NCT06747494

Knee OsteoarthritisHip Osteoarthritis

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 26, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Erector Spinae Plane Block Vs. IPACK Block with Adductor Canal Block for Total Knee Arthroplasty

Inclusion Criteria

Exclusion Criteria

A Phase Ib Study to Evaluate the Efficacy and Safety of HRS-2129 in Patients With Knee Osteoarthritis

General vs Spinal in Total Joint Arthroplasty (TJA)

A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

ROAM OA: Functional and Patient Reported Outcomes Wearing a Knee Brace for Unicompartmental OA

Knee Osteoarthritis Rehabilitation Through Rotational Inertia

Cryoneurolysis Prior to Total Knee Arthroplasty (CRYO-TKA Trial)