Loading clinical trials...
Loading clinical trials...
Vestibular ASsessment In Children - Balance Function in Normal Children and Specific Risk Groups (VASIC)
The goal of this prospective cohort study is to investigate the vestibular function in children with unilateral or bilateral sensorineural hearing loss. The main hypothesis of the study is that abnormal vestibular test results will be found in 20-30 % of the children with sensorineural hearing loss. The participants will be children in the age of 3-10 years with sensorineural hearing loss. The test protocol consists of questionnaires and vestibular and postural assessments.
Balance problems in children are an overlooked issue in the Danish healthcare system. Dysfunction of the vestibular system, i.e. vestibular dysfunction (VD), can have significant consequences for children's development and quality of life. In particular, children with sensorineural hearing loss are at risk of developing VD. Hence, VD has been reported in 14 % to 91 % of children with sensorineural hearing loss. The close anatomical and embryological relationship between the hearing system and the vestibular system may of course explain this correlation. The investigators aim for a child friendly and reliable vestibular test protocol in the study. According to the investigators studies as well as international reports, the investigators have chosen a vestibular test protocol with Video Head Impulse Test (v-HIT), cervical and ocular Vestibular Evoked Myogenic Potential (c and oVEMP) as the tests are feasible, valid, and child friendly. To evaluate overall balance ability, the children are tested on a Computerized Dynamic Posturography. The aim of the study is to investigate the vestibular function in children with unilateral or bilateral sensorineural hearing loss. Hypothesis: The investigators expect that abnormal vestibular test results will be found in 20-30 % of the children with sensorineural hearing loss. Methods: The study is a prospective cohort study. Participants are a prospective, unselected group of children in the age of 3-10 years with either unilateral or bilateral sensorineural hearing loss. The participants are recruited at The Audiologic Clinic at Viborg Regional Hospital, Denmark. All participants will go through a test protocol consisting of questionnaires and vestibular and postural assessments. The primary endpoints are results of v-HIT, c and oVEMP, and posturography, which are compared to normative values. The secondary endpoints are prevalence of vestibular dysfunction and mean total Dizziness Handicap Inventory for patient caregivers (DHI-PC) score. A number of variables are collected such as demographics, developmental milestones, family history with focus on hearing and balance.
Age
3 - 10 years
Sex
ALL
Healthy Volunteers
No
Gødstrup Regional Hospital
Herning, Denmark
Start Date
August 20, 2025
Primary Completion Date
August 1, 2028
Completion Date
December 1, 2028
Last Updated
August 26, 2025
48
ESTIMATED participants
video Head Impulse Test
DIAGNOSTIC_TEST
Cervical Vestibular Evoked Myogenic Potential
DIAGNOSTIC_TEST
Ocular Vestibular Evoked Myogenic Potential
DIAGNOSTIC_TEST
Computerized Dynamic Posturography
DIAGNOSTIC_TEST
Dizziness Handicap Inventory for patient caregivers
OTHER
Lead Sponsor
Gødstrup Hospital
NCT06323226
NCT05674786
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and Conditions