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Focused Suicide Prevention Strategy for Youth Presenting to the Emergency Department With Suicide Related Behaviour: A Multi-site Randomized Controlled Trial
Suicide is the leading cause of death due to illness among Canadian youth, claiming more lives than any medical illness, including cancer. Suicide prevention is possible, and early intervention is needed. The investigators will examine the effectiveness of a previously-piloted, ED-based suicide prevention intervention, across Canadian sites, using a randomized clinical trial design. The investigators will determine whether the patient- and family-centered intervention is more effective than enhanced usual care in reducing suicide-related behaviors in 330 youth at high-risk of suicide.
This is a Multi-site Randomized Controlled Trial of a patient- and family-centered suicide prevention intervention added to usual care (SAFE + UC) for adolescents aged 12 to 17 years who present to the Emergency Department (ED) with suicidal ideation or suicide risk behaviours. The investigators will determine whether the SAFE + UC intervention is more effective than enhanced usual care (telephone navigation + UC) in reducing suicide-related behaviors in 330 youth at high-risk of suicide across Canadian sites. SAFE + UC is a 6-week, standardized, manualized outpatient program that teaches participants to the skills to manage suicidal thoughts and impulses effectively. The family component addresses conflictual relationships that may be present in the family as well as improving family communication. Telephone navigation (NAV) + UC consists of up to 6 weekly telephone calls to ensure that the participant has connected with community resources suggested by the ED team and provide additional resources as needed.
Age
12 - 17 years
Sex
ALL
Healthy Volunteers
No
Alberta Children's Hospital - Alberta Health Services & University of Calgary
Calgary, Alberta, Canada
McMaster Children's Hospital - Hamilton Health Sciences
Hamilton, Ontario, Canada
Trillium Health Partners
Mississauga, Ontario, Canada
The Hospital for Sick Children
Toronto, Ontario, Canada
Start Date
March 1, 2021
Primary Completion Date
November 30, 2025
Completion Date
December 31, 2025
Last Updated
September 18, 2025
330
ESTIMATED participants
SAFE Intervention
BEHAVIORAL
NAV (Telephone Navigation)
BEHAVIORAL
Lead Sponsor
The Hospital for Sick Children
Collaborators
NCT07025720
NCT07432438
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
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