Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Regina Elena Cancer Institute
Patients enrolled for the study, according to eligibility criteria, undergo breast conserving surgery followed by adjuvant 10-fraction whole breast irradiation with a risk adapted simultaneous-integrated boost dose at the level of the tumour bed according to clinical and pathological risk factors.
Age
18–any
Sex
FEMALE
Healthy volunteers
Accepted
You may be eligible if
Histologically proven invasive or in situ unifocal adenocarcinoma of the breast
Breast conserving surgery
Pathological pTis G3, pT1-2 any Grade, pN0 or pN0(sn) (isolated tumor cells \[i+\] allowed) pN1mic, M0 stage
Postoperative negative (no ink) final surgical margins
Patient requires a whole breast radiotherapy plus a tumor bed boost
Female patients aged ≥ 18 years of any menopausal status
ECOG performance status 0-2
You may not be if
Past history of malignancy except basal cell skin cancer and CIN cervix uteri or non-breast malignancy allowed if treated with curative intent and at least 5 years' disease free
Mastectomy
Concomitant chemotherapy (primary or sequential chemotherapy allowed) (Chemotherapy and radiotherapy must be separated by a minimum of 2 weeks). (Patients receiving neo-adjuvant chemotherapy are not excluded)
Known disorders associated with a higher risk for complications following radiotherapy such as collagen vascular disease, dermatomyositis, systemic lupus erythematosus or scleroderma
Any psychological, familiar, sociological or geographical condition potentially hampering compliance with the study protocol and follow-up schedule
Any serious uncontrolled medical disorder, non-malignant systemic disease, or active uncontrolled infection. Example include but are not limited to uncontrolled ventricular arrhythmia, recent (within 3 months) myocardial infarction or uncontrolled major seizure disorder
Pregnant or lactating patients
Presence of ipsilateral breast implant
Prior breast or thoracic radiotherapy for any condition
Clareo Health | External Hypofractionated Radiotherapy With Simultaneous Integrated Boost in Early Breast Cancer Patients
