Age

35–85

Sex

ALL

Healthy volunteers

Not accepted

Fontaine I-IV class symptoms
Confirmed diagnosis of LEAD
Age 35-85
Has to have at least of the following: hypertension, diabetes, coronary artery disease or the patient smokes

Age \<35 or \>85 years
BMI ≥40 kg/m²
Known heart failure in history
Any acute or chronic autoimmune or rheumatic disease
Cardiac structural disease in history: inflammatory, infiltrative diseases, nonischemic cardiomyopathies
Acute coronary syndrome in last 3 months
Moderate to severe cardiac valvular disease
Cardiac valvular disease operative/invasive treatment in history
Cardiac implantable electronic device (CIED)
Transitory ischemic attack or stroke in last 3 months
Severe COPD (GOLD C or D)
Moderate to severe asthma (according to GINA 2022 criteria)
Untreated hypertension (noninvasive blood pressure measurement ≥180/110 mmHg during recruitment)
Chronic severe kidney dysfunction (eGFR \<30 ml/min/1,73 m²)
Malignant tumor with radiation treatment to thorax, oncologic or biologic treatment in history
Chronic hematologic disease (except for anemia)
Severe liver dysfunction
Malignant tumor with \<5 years of remission
Acute or chronic infectious disease
Anemia with hemoglobin \<80 g/L

Myocardial Dysfunction Evaluation in Lower Extremity Arterial Disease Patients With Deformation Analysis