Scheduled to undergo a cardiac surgical procedure with cardiopulmonary bypass
Planned postoperative admission to the intensive care unit (ICU)
You may not be if
Allergy or hypersensitivity to dexmedetomidine or the placebo study medication
Preexisting diagnosis of Alzheimer's Disease or Related Dementia, severe cognitive impairment or delirium at baseline
Severe liver failure (Child-Pugh score \> 5)
Severe deficit(s) due to structural or anoxic brain damage
Undergoing a surgical procedure requiring total circulatory arrest
SARS-CoV-2 positive or symptomatic (e.g., fever, cough, loss of taste/smell)
Blind, deaf, or unable to communicate in English
Patients experiencing circumstances for which long-term follow-up might be difficult (e.g., homelessness, active psychotic disorder, or substance abuse)
Co-enrollment in other interventional studies that, in the opinion of the site investigator and/or PI, might interfere with study participation, collection, or interpretation of the study data
Clareo Health | Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)
