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Impact of Preoperative Respiratory Strength Training on Postoperative Health for Heart Transplant Recipients
This research study is investigating whether completing breathing exercises before surgery helps heart transplant patients recover after surgery. Previous studies have shown that breathing exercises can improve breathing, cough, and swallow function in patients with other diseases/conditions. The current study will investigate the impact of a preoperative respiratory muscle strength training program on breathing and cough function, swallow function, patient-reported eating and swallowing fatigue, and health outcomes in individuals undergoing heart transplantation. Participants will: * undergo tests of breathing, cough, and swallow function * complete questionnaires about the treatment, their swallow function * complete breathing exercises daily
This study will involve three in-person research evaluations to our lab or in the hospital that will last 45 minutes- 1 hour and will consist of a screening, breathing and cough testing, swallow function testing, and completion of questionnaires. Following the initial research evaluation, individuals will complete daily exercises of active or sham respiratory muscle strength training for several weeks with one telehealth or in-person session per week. The exercises will take 10-15 minutes to complete, and individuals will fill out training logs daily. Prior to transplantation and after completion of the breathing exercises, individuals will undergo a second research evaluation. Then, following surgery, individuals will undergo a third research evaluation and outcomes will be tracked via the electronic health records system.
Age
18 - 90 years
Sex
ALL
Healthy Volunteers
No
Vanderbilt University Medical Center
Nashville, Tennessee, United States
Start Date
May 17, 2024
Primary Completion Date
April 1, 2026
Completion Date
March 31, 2027
Last Updated
May 31, 2025
90
ESTIMATED participants
Active respiratory muscle strength training
BEHAVIORAL
Sham respiratory muscle strength training
BEHAVIORAL
Lead Sponsor
Vanderbilt University Medical Center
NCT07217938
NCT07255352
Data Source & Attribution
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